Expected Impacts

BIOTOOL-CHF gathers major European heart failure and big data analysis experts to provide an innovative approach to the management of heart failure with reduced ejection fraction which is one of the most frequent, costly and deadly pathological conditions in Europe. The BIOTOOL-CHF will provide technological solutions to personalise current treatment options and reduce disease burden.

Set of validated biomarkers to estimate congestion and related clinical outcomes of patients with chronic heart failure with reduced ejection fraction

AI-derived algorithm from multiparametric analysis of patients characteristics to identify congestion and to predict prognosis

Decision-making tool to implement management of fluid retention by means of loop diuretics

Prototype of Point of Care companion diagnostic to assess biomarkers concentrations

Strategy plan to comply for CE marking of the Companion Diagnostic